Multiple Sclerosis

Background

Multiple Sclerosis (MS) can be caused by a host of different triggers that then stimulate an immune response against your own nerve coatings (called the myelin sheath — like the plastic cover over a wire). It is considered an autoimmune disease, where your immune system mistakes your nerves for an outside invader and attacks them.

Though the cause is unknown, I suspect it is a common endpoint to a host of problems, including viral or antibiotic sensitive infections, toxicity (chemical or heavy metal), or other unknown causes. Vitamin D deficiency is a likely major player as well. Vitamin D comes from sunshine and helps regulate immune function. In fact, MS is much more common in people who live further from the equator, where people get less sunshine.

Early Symptoms

Though the diagnosis usually becomes clear as the MS progresses, it may not be in the beginning. A person with MS can suffer almost any neurological symptom or sign. Symptoms that suggest MS include transient loss of vision in one eye, or transient localized paralysis, or loss of sensation (to where you can stick a needle into the area without feeling it). In some people it is progressive and in others the attacks come and go.

Treatments

Standard Treatments

Some standard treatments (such as COP 1 or Copolymer 1) are worthwhile. Others, such as interferon, may help but have a lot of side effects. Your neurologist can best guide you on these.

Holistic Approaches

Hidden infections

While deciding on standard therapy, try adding holistic approaches. These recognize that a number of viral and antibiotic sensitive infections (that cannot be readily detected on standard testing) may trigger the MS. Consider a trial of antivirals (e.g., Valcyte) and/or antibiotics, empirically, to see if they help. In a study in which the antibiotic doxycycline (the same antibiotic given to kids for years to treat acne) was added to interferon, the antibiotic improved the interferon’s effectiveness.

Detoxification for heavy metals

Detoxification for heavy metals is also reasonable in MS, using intravenous EDTA chelation. It’s controversial, but it’s reasonable for MS or ALS.

Recommended Supplements

PEA

Research is mounting that for neurodegenerative diseases in general, especially in the presence of chronic pain, a supplement called PEA (Palmitoylethanolamide) 600 mg a day can be quite remarkable in both decreasing pain and regenerating nerve and brain cells. It takes three months to start seeing the effect however, so give it time.

Vitamin D

Take 4,000 units of vitamin D daily, as low vitamin D is likely a major contributor to MS.

Multivitamin powder

Take a good multivitamin powder to relax tight muscles, improve energy, and protect brain function. The Energy Revitalization Drink Mix is a good choice for this as it includes the magnesium for muscles, B12 to help nerve healing, as well as glutamine, glycine and NAC to raise glutathione. It also contains 1,000 units of vitamin D.

Estriol

In women, the bioidentical estrogen Estriol (8 mg a day — a level mimicking pregnancy) resulted in marked improvements in symptoms and MRI scans in one study (although symptoms recurred after stopping treatment). Women actually have less relapses during pregnancy.

Other Therapies & Advice

For Bladder Spasticity

The herb angelica and magnesium 200 mg a day (present in a good multivitamin powder), can both help restore healthy bladder function.

MS Related Fatigue

This can be helped by the S.H.I.N.E. protocol discussed under fibromyalgia.  And if you have widespread pain and trouble sleeping, then you likely have a secondary fibromyalgia caused by the MS. The medication Amantadine can also help MS-related fatigue.

Find a health practitioner

Your neurologist will be able to guide you on standard care. For a holistic physician near you, visit the The Institute for Functional Medicine®. Then do a phone consultation with Dr. David Perlmutter of BrainRecovery.com who can guide your holistic physician.

More Information Online

Articles on Multiple Sclerosis by Dr. T